Whats new with AndroSeries v3?

Its been nearly a year since the initial release of the AndroSeries products, yet we are back with major changes, outdoing ourselves all over again.

We hope you enjoy all the improvements of AndroSeries v3.

Major improvements for ALL products:

  1. Once per day dosing: Semi-solid liquid delivers timed released androgens for convenient dosing.
     
  2. Reduced testicular shrinkage: 24hr timed release effect mimics the body’s natural androgen release. This reduces testicular shutdown and improves recovery time.
     
  3. No lethargy or brain-fog: We improved the ratio of GABAergic isomers to eliminate the occurrence of general "tiredness" and "lethargy" reported by certain AndroHard and AndroMass users.
     
  4. Improved retention of libido: The improved ratio of GABAergic isomers, and removal of Super-1-DHEA  supports a more normalized libido. (AndroMass & AndroHard)
     
  5. Increased correlation of "Testosterone equivalent" to real world results: Case reports of AndroSeries v3 revealed a strong correlation to our re-calculated "testosterone equivalent" values.
     
  6. Safety data backed by comprehensive blood data:  Over 15 healthy male subjects where recruited for 4-8 week cycles of the AndroSeries v3 products for comprehensive pre, during and post blood analyses. (e.g. liver, kidney, cholesterol, metabolic function, etc) Full case reports can be found on the product pages.
     
  7. Eliminated/reduced post dose nausea: Previous generation of AndroSeries v2 had a 5-10% likelihood of causing immediate nausea or vomiting for individuals sensitive to the grapefruit content. Now, AndroSeries v3 contains a timed-release dose of organic grapefruit, showing elimination of negative reactions in sensitive individuals.
     

Additional  improvements for specific products:

  1. AndroLean: New AndroLean is up to 4x stronger than the previous version. The addition of high dosed 11-oxo-testosterone (Super-11-DHEA) dramatically increases the anabolic potency, while 2x more Super-7-DHEA enhances the thermogenic power.
     
  2. AndroHard: New AndroHard has 2x more active ingredient than the previous version. The balanced mix of GABAergic isomers of epiandrosterone and androsterone for eliminates feelings of  "tiredness" and "lethargy" — while enhancing mental clarity and aggression.
     
  3. AndroMass: New AndroMass is up 2x stronger than the previous version. The balanced mix of GABAergic isomers of epiandrosterone and androsterone for eliminates feelings of "tiredness" and "lethargy" — while enhancing mental clarity and aggression.
     

New "Testosterone Equivalent" values:

For simplicity sake we have calculated the activity of all the AndroSeries products in "testosterone equivalents" — which represents the total combined androgenic, anabolic and estrogenic bio-activity for the 24hr period.

We chose "testosterone equivalents"  for AndroSeries products because it can be easily comprehended and compared to other forms of testosterone  — Even though testosterone is not the main mechanism by which the AndroSeries products work. Remember, there are dozens of androgens in the body which function very similar to testosterone, and these are the androgens that are responsible for the effects of the AndroSeries.  (e.g. androstenedione, androstenediol, ect)

The following values have been established per softgel –

  • AndroDrive – 217 ng/dL
  • AndroHard – 375 ng/dL
  • AndroLean – 334 ng/dL
  • AndroMass – 450 ng/dL
  • AndroBulk – 450 ng/dL

Keep in mind, this testosterone equivalent value does not tell you how androgenic, anabolic or estrogenic each product is in relation to each other. It is only a general average of "testosterone-like" effects. If you would like to see how the effects of each AndroSeries compares, please visit our AndroSeries comparison page here – AndroSeries Effects Chart

New AndroStat & AndroStacker:

To help you find out your current testosterone level, we built the AndroStat.

Once you get your testosterone levels, begin to build the perfect stack with the AndroStacker.

 

We've taken the "testosterone equivalent" values of our AndroSeries products and built them into the AndroStacker program. This allows you to build a stack of AndroSeries products and see the benefits, side-effects and "androgen zone" — so you can make sure you are taking the optimal dose for your custom goals with minimal side-effects.

 

Questions?

Talk to a product specialist in Live Chat

Call us – 1-503-841-6702
Email us – info@primordialperformance.com
Or get registered for our free forum

 

 

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Avoid Milk and Sugar for a Clear Complexion

Acne sucks and no one likes it….

Why is it so prevalent in our present times and how can we rectify this current epidemic? 

Well, an interesting, yet alarming tidbit is that currently 85% of our adolescents are experiencing acne as well as men and women in their twenties. It is common knowledge to assume the main culprit of this problematic condition is hormone related, and pubescent teens are pulsing the greatest hormone production of their lives during these times. Fluctuating hormone levels do elicit side effects such as acne, BUT there might be some environmental factors that are magnifying these effects.

Let's face it, our current nutritional guidelines that are being recommended is insanity. High carbohydrates, low fat and low protein based nutrition. Also, how many teenagers do you know that adhere to meticulous nutritional regimens and properly stay hydrated and avoid excessive empty calories and other "anti-nutritious" foods?

I would guess your answer is "not many." 

Recent research has demonstrated that the consumption of milk and dairy-based products are major players in contributing to the acne epidemic we currently face. Milk is loaded with hormones and growth factor's such as; bGH (bovine growth-hormone) IGF-1 and also trigger's insulin release. Elevated plasma IGF-1 levels from milk further exacerbate endogenous production of hormones that are already high during puberty. The presence of 5a-pregnanedione, 5a-androstanedione and other precursors of 5a-dihydrotestosterone add to the potency of milk to increase the formation of acne. 

Most cheaper milk products currently available derive milk from prenatal cows, which are jacked full of hormones from the pregnancy. DHT is then transferred into the milk product and then consumed by adolescents and young adults in conjunction with their sugary morning cereal!

(High consumption of milk & high glycemic carbs like French fries can trigger acne)

 Let's consider the role DHT plays on the production of sebum. As DHT gets elevated from milk consumption, new sebocytes are produced which ignite more sebum production, which trigger more acne. This vicious cycle is even further magnified by a diet rich in sugar and high-glycemic carbohydrates. Sugary foods with high glycemic loads will induce abrupt pulses of insulin production by the pancreas. The bolus amount of insulin will also spike IGF-1 levels, which are already high in teens and young adults to begin with. 

IGF-1 is a mitogen and after IGF-1 attaches to its receptor sites in various tissues, it induces cell division, cell proliferation, and prevents cell apoptosis (which is the death of cells) Keratinocytes (epidermis cells), sebocytes (epithelial cells) as well as the adrenals and gonads, which get stimulated by IGF-1 production.

Here is something to think about – 

Notice how you will occasionally see what appears to be a young women, meaning fully developed and looks "of age,' then your jaw drops when you realize that this young female is 12 or 13 years old…..

There is sound reasoning for this mind-boggling occurrence. It would be unethical and twisted to inject 8-9 year old females with several hormones such as; estrogen, progesterone, prolactin, testosterone, IGF-1, rHGH and various other growth factors right? Well drinking milk in high amounts is doing just that – saturating their endocrine system with a multitude of growth spurting, powerful hormones. There is research indicating that average height's and body weights of young females have increased dramatically in the last 50 years. I suppose drinking a substance that contains over 59 bio-active hormones can have such an affect.

Back to the subject at hand pertaining to dairy & sugar promoting a greater incidence of acne.

What can be done?

Well, for starters stay away from milk or dramatically decrease its consumption. I would suggest exchanging milk for Almond Milk or Coconut Milk. These 2 substitutes are low in calories and do not contain unpredictable hormonal fluctuations and contain MCT fatty acids (coconut milk) & Monounsaturated fatty acids (almond milk). Trust me – YOU CAN STILL ENJOY CEREAL! Of course to keep insulin under control and igf-1 levels stable, the cereal selection should be scored low on the glycemic index and be enriched with dietary fiber

Some useful herbal based supplements to take for insulin control would be gymnema sylvestre, banaba leaf, bitter melon and cinnamon. For pharmaceuticals Metformin also known as Glucophage would lower IGF-1 levels and keep insulin and blood sugar at low baseline levels.

If persistent acne stays with you well into adulthood, you need to take charge immediately and get your IGF-1 levels down. As adulthood acne may be considered a health risk factor for increased risk of cancer, which will require dietary modifications and proper natural or pharmaceutical treatment of insulin-sensitizing agents.

As always, I write these articles to give you (the reader) something to think about and consider. Do I personally stay away from all dairy products? I would be a liar if I said yes. I eat cottage cheese, low-fat mozzarella cheese, Greek yogurt (occasionally), and as a competitive Bodybuilder, various forms of dairy protein in powder form is consumed at key times of the day. I do however; avoid milk consumption and use almond & coconut milk instead. 

If you suffer with mild to severe acne, try eliminating the consumption of dairy products and also monitor your carbohydrate intake, namely simple sugars. I personally adhere to high fluid intake to constantly stay hydrated and to flush toxins out of the body. I find when I drink 2 gallons of water per day, my complexion improves dramatically.

 

References:

1.)Danby FW.Nutrition and acne.Clin Dermatol. 2010 Nov-Dec;28(6):598-604.

2.)Melnik BC, Schmitz G.Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris.Exp Dermatol. 2009 Oct;18(10):833-41. Epub 2009 Aug 25.

3.)Melnik BC.Evidence for acne-promoting effects of milk and other insulinotropic dairy products.Nestle Nutr Workshop Ser Pediatr Program. 2011;67:131-45. Epub 2011 Feb 16.

4.)Melnik B.[Acne vulgaris. Role of diet].Hautarzt. 2010 Feb;61(2):115-25. 

5.)Melnik B.Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies.J Dtsch Dermatol Ges. 2009 Apr;7(4):364-70. Epub 2008 Feb 20.

Cynostane

Diagram of molecule

Chemical Name(s):

2-cyano-17a-methyl-17b-hydroxy-androstan-3-one
2-cyano-17a-methyl-17b-hydroxy-androst-3-one (incorrect name)
Chemical Formula: C21H31NO2
Molecular Weight: 329
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 40%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
40-50mg/day standalone
20-30mg/day when stacking
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

2-cyano-dromostolone is a 17aa molecule relatively new to the scene with very few reviews as of yet.

It has a cyano group attached to the 2 position. The chemical structure is the same as methyldrostanolone (Superdrol), except it has a CN group on the 2 position instead of a methyl group. It is a C-17aa steroid and it will be liver toxic. Although, due to the lack of the 4-ene on ring A and lack of 2-methylation, liver toxicity may be reduced relative to a di-methylated steroid such as Superdrol.

So far, feedback is very limited for this compound. However results would be expected to be fairly lean as this compound cannot convert to estrogen. Based on the chemical structure the anabolic potency would appear to be fairly potent with moderate androgenic potency.

At the time of this writing there was only one manufacturer to bring this product to the market and there seems to have been a nomenclature mistake on the labeling for this steroid. The chemical name contains the term “androst”, assuming that there is some sort of ene group on ring A. But there does not seem to be such mention of an ene group on ring A. Therefore, the term androst should be androstan. But if this is the case, the 2-cyano group needs to be stated as alpha or beta. This makes a big difference, since usually C2-alpha groups are significantly more effective than beta.

There are studies about other 2-cyano steroids such as 2-cyano-DHT and 2-cyano-progesterone. In separate studies, one done on dogs, it was seen that both of these 2-cyano steroids caused inhibition of 3b-HSD enzyme. This inhibition would cause severe adrenal suppression. This is a very unsafe inhibition. Whether it occurs in this cyano steroid is unknown, but users need to be aware of this possibility.

Common Clones:

Cynostane by Anabolic Innovation


Related Discussion

The Official Cynostane Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Dimethazine

Diagram of molecule

Chemical Name(s):
17beta-hydroxy 2alpha,17alpha-dimethyl 5alpha-androstan 3-one azine
Chemical Formula: C42H68N2O2
Molecular Weight: 632
CAS: NA
Q Qatio: 2.2
Anabolic #: 210
Androgenic #: 95
Oral Bioavailability: Estimated at 40%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
20-40mg/day standalone
10-20mg/day when stacked
Average Cycle Length: 2-4 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Dimethazine is actually two steroid molecules bound together by a nitrogen atom. Upon ingestion, stomach acid separates the two steroid molecules that closely resemble methyldrostanolone (Superdrol).

Although dimethazine appears very similar to methyldrostanolone, the presence of a nitrogen at the 3rd position appears to increase its androgenic potency relative to its anabolic potency (210/95 compared to 400/20 for methyldrostanolone). Therefore, dimethazine could be considered a slightly weaker form of methyldrostanolone, but perhaps less likely to cause gyno related issues because of its higher relative androgenic value (and ability to antagonize estrogenic effects).

Otherwise, all side-effects and benefits could be considered relatively the same as methyldrostanolone. Liver toxicity and its associated side-effects of general sickness should still be expected, especially if the liver becomes compromised. Using a liver protecting supplement prior to and during a cycle of Dimethazine would be very important.

The quick gains in size and strength will likely be accompanied by increases in intense back pumps, high blood pressure, shortness of breath and oily skin. Vascularity would also be expected to improve with this compound due to the increase in extra-cellar water and possible decrease in subcutaneous water weight.

Because this compound is a 17aa oral, it is not recommended to be stacked with other 17aa oral steroids.

Common Clones:

Dymethazine by IForce


Related Discussion

The Official Dimethazine Thread
Posted by Eric

References

“Oral administration of an anabolic-androgenic steroid dimethazine increases the growth and food conversion efficiency and brings changes in molecular growth responses of carp (Cyprinus carpio) tissues”

LONE K. P. (1) ; MATTY A. J. ;
Nutrition reports international

“Contribution to the study of the proteoanabolic effects of dimethazine. (Clinical research)”
CEI C, ANSELMI G.
Gazz Med Ital. 1963 Feb;122:57-61

“A new steroid having proteo-anabolic action: dimethazine.”
DE RUGGIERI P, MATSCHER R, GANDOLFI C, CHIARAMONTI D, LUPO C, PIETRA E, CAVALLI R.Arch Sci Biol (Bologna). 1963 Jan-Mar;47:1-19.

Desoxymethyltestosterone (Pheraplex, DMT, Madol)

Diagram of molecule

Chemical Name(s):
17a-methyl-etioallocholan-2-ene-17b-ol
17a-methyl-5a-androst-2-ene-17b-ol
Chemical Formula: C20H32O
Molecular Weight: 288
CAS: NA
Q Qatio: 6.5
Anabolic #: 1200
Androgenic #: 187
Oral Bioavailability: Estimated at 40%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: ~9 hours
Legal Status (US): Listed as a controlled substance
Average Dose:
40-60mg/day standalone
10-30mg/day when stacked
Average Cycle Length: 4 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Desoxymethyltestosterone (DMT) is a 17aa steroid with equal toxicity as other 17aa oral steroids. While nearly all anabolic steroid molecules have a 3-keto group, Desoxymethyltestosterone lacks it, and has a 2-ene structure. This compound is readily active and does not require conversion.

DMT does not aromatize, nor does it appear to have any progestational activity, yet some users still experience gyno symptoms and bloat from this compound. This is likely related to the lack of androgenic potency from this compound (to antagonize the effect of estrogen). DMT may also contribute to gyno by displacing estrogen (and testosterone) from SHBG. It has also been proposed that DMT can inhibit 11b-hydroxylase and thus increase intracellular sodium and water retention by building up mineralcorticoid levels.

Depending on where you look, DMT has been reported to be 2-12 times more anabolic and 0.4-2 times as androgenic as methyltestosterone. It has been proposed that DMT is a naturally occurring substance because it has an almost identical structure to delta 2-androstenol, a naturally occurring pheromone in mammals. However, being a 17aa steroid hormone makes it synthetically altered and not naturally occurring. Either way, it is now a controlled substance in the United States.

Users should expect significant strength increases, weight gain, and bloat. Weight gains upwards of 20lbs in 4-6 weeks are not unheard of with this compound. The most obvious physical side effects will be strong muscular pumps, shortness of breath, high blood pressure, oily skin, and bloating. If users wanted to minimize toxic effect on the liver or other side effects, DMT could be used at doses as low as 10mg/day for a decent effect.

Being that this compound is methylated, it should not be stacked with other methylated compounds. Having moderately low androgenic activity, DMT may negatively affect the libido and erectile function. This side effect could be offset by stacking DMT with testosterone or one of its non-aromatizing metabolites to preserve DHT levels.

Common Clones:

P-Plex by Competitive Edge Labs (CEL)
Phera-Plex by Anabolic Xtreme
Nasty Mass by Purus Labs
Phera-VOL by Engineered Sports Technology (EST)
PheraFLEX by IForce
D-Stianozol by Nutracoastal
Pheradrol by PH Design
P-Max by Growth Labs
Phera-MAX by Generic Labs
Phera-BOL by Juggernaut Nutrition
Phera-Mass by Kilo Sports
Straight Phlexed by Black China Labs

Related Discussion

The Official Desoxymethyltestosterone (Pheraplex, DMT, Madol) Thread
Posted by Eric

References

“Characterisation of the pharmacological profile of desoxymethyltestosterone (Madol), a steroid misused for doping”

P. Diel, A. Friedel, H. Geyer, M. Kamber, U. Laudenbach-Leschowsky, W. Schänzer, M.
Thevis, G. Vollmer and O. Zierau
Toxicology Letters; Volume 169, Issue 1, 28 February 2007, Pages 64-71

norDHEA

Diagram of molecule

Chemical Name(s):

5-estren-3b-ol-17-one
Nordehydroepiandrosterone
Chemical Formula: C18H26O2
Molecular Weight: 274
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 4%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
300-600mg/day standalone
200-300mg/day when stacked
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

norDHEA is a non-methylated (non-17aa) pro-steroid. (naturally occurring in trace amounts in humans)

norDHEA can convert to the illegal anabolic steroid nandrolone by converting to norandrostenediol/norandrostenedione, and then to nandrolone. Nandrolone is known to have stronger anabolic effects than testosterone, yet weaker androgenic effects.

norDHEA will aromatize to estrogen less than regular DHEA, but because it is a nor compound it lacks strong androgenic metabolites. For instance, after nandrolone interacts with 5a-reductase, the metabolite dihydronandrolone (DHN) is formed, which is a weaker nor-version of DHT.

Ironically, the lack of estrogen conversion from norDHEA is probably balanced by the lack of androgenic potency and progestational effects, which makes the possibility of bloating and experiencing gyno about as likely as with regular DHEA.

One difference between norDHEA and DHEA that should be considered is the fact that norDHEA will have less androgenic effects, which may pose less risk of androgenic related hair loss and/or acne. This may be a smart choice for some men, and a decent choice for women looking for a moderately anabolic compound without much androgenic effect. (to avoid masculinizing side-effects)

Because of the low bio-availability, high doses must be used to notice gains in lean muscle mass and strength. Even with higher doses, the gains will be mild to moderate. Some bloat should be expected from the estrogenic and progestational effects of the nor-steroids. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.

Like the other DHEA derivatives, norDHEA would be useful in a transdermal application since the enzymes needed for the conversions to more powerful metabolites are concentrated in the skin and absorption through the skin using a good transdermal delivery cream could allow for 5-10x higher absorption than oral.

This compound would stack well with almost any other steroid, except those with progestational activity.

Common Clones:

Decavol by Advanced Muscle Science (AMS)


Related Discussion

The Official norDHEA Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Dienedione (Tren)

Diagram of molecule

Chemical Name(s):

19-norandrosta-4,9-diene-3b,17b-dione
estra-4,9-diene-3b,17b-dione
4,9 Estra
Chemical Formula: C18H22O2
Molecular Weight: 270
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 20%
AR Binding Affinity: 5
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Listed as a controlled substance
Average Dose:
100-200mg/day standalone
50-100mg/day when stacking
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Dienedione is a non-methylated steroid that converts to a steroid known as 17b-hydroxy-estra-4,9,(10)-dien-3-one (dienolone).

Although dienedione may have some anabolic activity on its own, it gets most of its effects from conversion to dienedrone by interaction with 17b-HSD. This steroids overall effects are somewhere between trenbolone and nandrolone.

Dienedione is known for causing night sweats via its powerful thermogenic effects similar to trenbolone. This thermogenic effect makes dienedione an excellent choice for dropping bodyfat during cutting cycles.

As a 19-nor this compound has decent progestational effects which may lead to gyno symptoms, libido loss and aggressive mood swings. Part of the reason gyno may be a problem with this compound is also because it lacks androgenic potency and down-regulates DHT levels during cycle, which is the body’s natural estrogen blocker.

Dienedione does not convert to estrogen, although it can still lead to the side-effects mentioned above. Because this compound is not 17aa liver toxicity is not really a concern. However some users have reported elevated liver enzyme values during cycle, although this could be related to other factors.

Users usually experience rapid gains in strength and aggression, followed by significant weight gain after several weeks. The results are generally fairly lean with only minor bloat due to the progestational effects.

Dienedione can be used as a standalone. In an effort to prevent libido loss and gyno, it may be stacked with testosterone or one of its non-aromatizing metabolites to help keep DHT levels elevated during cycle.

Common Clones:

Dienedrone by Advanced Muscle Science (AMS)
Liquidrone UTT by Advanced Muscle Science (AMS)
X-Tren by Competitive Edge Labs (CEL)
Tren Xtreme by American Cellular Labs
Tren 250 by Genetic Edge Technologies (GET)
Trena by Nutracoastal


Related Discussion

The Official Dienedione (Tren) Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

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