Are you Ready for the Andro Series?

The release of the Andro Series Project is right around the corner and is going to be a steroidal breakthrough in the supplement industry. Each compound is a Metabolic Steroid and will elicit a host of effects such as; improved metabolic rate for losing body fat, increased anabolism for accruing lean muscle mass, heightened sexual prowess for intimacy, and improved self-confidence. What there won’t be are numerous hazardous side effects that are commonly seen with the current line of designer steroids and illegal anabolic steroids. The Andro Series has been meticulously formulated to avoid excessive stress on the liver, kidneys and heart. However, please don’t mistake a lack of side effects for a lack of results. Delivery is everything when it comes to a product being active and effective, and we have established the best in oral delivery and bio-availability.

Stack AndroMASS with AndroHARD for extreme muscular weight gain

I would like to prepare you for how to optimize and maximize your experience when incorporating the Andro Series products into your nutrition and training regimen. I would advise anyone who has experienced a training layoff due to injury, illness or laziness to first get back into the swing of things before utilizing hormonal supplementation. You will be growing regardless so it would give Andro Series a false sense of effectiveness. Once you have hit a training and nutrition plateau then it is time to implement a steroid cycle. Depending on your goals, whether it is ultimate muscle gain or extreme fat-loss you must choose the proper products to accommodate your target goal. For extreme muscular weight gain, stacking Andro Mass with Andro Hard would provide an ideal hormonal environment. The Andro Mass would be the “meat and potatoes” of the stack, yielding high conversions to Testosterone and DihydroBoldenone. Testosterone needs no description as it is the most widely used steroid available. It is known to enhance muscle mass, increase fat-loss, and raise sex drive. DihydroBoldenone is a 5-aplha-reduced form of the steroid boldenone. It elicits mild androgenic traits and is a potent anabolic. It has been reported to bind aggressively to the androgen receptor eliciting minimal androgenic side effects and substantial transcriptional gene activity that induces extreme muscle growth. The Andro Hard will convert into DHT at a high rate, so androgenic effects will be achieved. Andro Hard displays powerful characteristics such as: an increase in strength, sex drive, and mental focus for rigorous training sessions.

AndroMASS will induce –

  • High anabolic activity
  • No toxic side effects
  • Increased muscle hardness
  • Muscular weight gain
  • Superior delivery of hormones

AndroHARD will induce –

  • Profound vascularity
  • Gyno protection
  • Magnified sex drive
  • Increased aggression
  • Superior delivery of hormones

What is the optimal nutrition plan for this mass gaining cycle?

Now that you know how these 2 products can help you in your plight for extreme mass gaining, it is on you to implement proper training and nutrition to potentiate the effects of the steroid cycle. I will not expand too much on the nutritional aspect of utilizing this stack for muscular weight gain, but I will briefly touch base on a few key dieting recommendations. Make sure to structure your meals and plan ahead so you can stay consistent with no excuses. Create a nutrition plan that coincides with your body type. Meaning, if you are an ectomorph, you can get by with a higher influx of carbohydrates (400-600 grams) and dietary fat than an endomorphic body type. The mesomorph and endomorph would benefit greatly from a modest allotment of quality carbohydrates (150-300 grams) and using essential fatty acids for their fat sources. All body types would need to adjust their protein intake depending on body weight and their carbohydrate and dietary fat requirements. A good rule of thumb for mass gaining is to ingest 1.5 grams of protein per pound of body weight. You may ask, “Why only 1.5 grams?” That is because you have adequate fat and carbohydrates to spare the protein.

Which body type are you?


Next, we will go over the goal of extreme fat-loss. Andro Hard stacked with Andro Lean would be the weapons of choice to accomplish such a goal. The Andro Lean is equipped with Super-7-Dhea, which will increase fat loss 3 times more than diet and exercise alone. Super-7-Dhea will increase fat oxidation through the mitochondria from increased thyroid output from elevated T3 levels. However, thyroid stimulating hormone and T4 levels will remain unchanged, so thyroid suppression is not an issue. Super-5-Dhea is also included to keep testosterone levels elevated for muscle preservation and increased sex drive when going on a reduced calorie diet. The ectomorph body type once again can have more liberty with their carbohydrate allotment (200-300 grams) while cutting, but keep dietary fat lower so calories are in a deficit. Cardio is usually something ectomorphs don’t have to worry about, but for general health, it is recommended 3-4 times a week for at least 20 minutes. The mesomorph would diet best on medium to low carbohydrates (100-200 grams) incorporated around training, while ingesting protein with essential fatty acids at other meals of the day. Cardio performed 5 times a week, starting at 20 minutes a day is recommended. The endomorphic body type usually responds well to very low carbohydrate intake (30-75 grams) while keeping essential fatty acids in the diet. Cardio will be a key factor in getting lean with endomorph’s, so I would recommend starting off with 30 minutes a day, 6-7 times a week. When starting a cutting phase, protein intake should get ramped up since carbohydrates and fats are reduced. I recommend 2 grams of protein per pound of body weight and adjust accordingly from there. As far as weight training is concerned, I like to see people whether dieting or bulking to base their workouts around basic free weight movements. Squats, (back and front) dead lifts, (all variations) Incline barbell and dumb bell bench presses, standing barbell curls, and bent over barbell rows should all be staples if you have no injuries inhibiting you from executing such crucial exercises.

AndroLEAN will induce –

  • Increased active thyroid output (T3)
  • Increased fatty acid uncoupling
  • Mild conversions to testosterone
  • Non stimulant thermogenesis
  • Superior delivery of hormones

It should be no surprise that having your Post Cycle Therapy planned ahead of time is always recommended. You should never start a steroid cycle without having all ancillary products and post cycle products in your possession from the beginning. There are some very effective products that stand out when choosing a proper PCT protocol. If you choose a pharmaceutical, Toremifene would be a good choice. D-aspartic-acid also has proven itself effective alongside a natural SERM-like supplement, such as Trans-Resveratrol. I would recommend running your Post Cycle Therapy for at least 4 weeks to ensure adequate recovery of natural hormones.

Toremifene molecular structure shown above:

In closing, please understand that you need to plan your steroid cycles carefully and never go into it and “wing it.” Plot out your nutrition protocol, training regimen, and PCT accordingly. Keep in mind you are suppressing your endogenous production of natural hormones so make the absolute most of your next cycle.

References:

1.)Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schanzer W, Thevis M, Voller G, Zierau O, Diel P. 17beta-hydroxy-5alpha-androst-1-en-3-one(1-testosterone) is a potent androgen with anabolic properties, Toxicol Lett. 2006 Aug 20;165(2):129-55.
 

2.)Lam P. Ly, Mark Jimenez, Tian N. Zhuang, David S. Celermajer, Ann J. Conway, and David J. Handelsman,A Double-Blind, Placebo-Controlled, Randomized Clinical Trial of Transdermal Dihydrotestosterone Gel on Muscular Strength, Mobility, and Quality of Life in Older Men with Partial Androgen Deficiency. J. Clin. Endocrinol. Metab., Sep 2001; 86: 4078 – 4088.

3.) Christos S Mantzoros, Emmanuel I Georgiadis, head, Endocrine Unita, Dimitrios Trichopoulos, professor and chiefb, Contribution of dihydrotestosterone to male sexual behavior. BMJ 1995; 310 : 1289 (Published 20 May 1995)

4.)Bobyleva V, Bellei M, Lardy H. The effects of the ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: Possible relationship to thermogenesis. Arch Biochem Biophys 1997;341:122-128.

5.)Bosy TZ, Moore KA, Poklis A. The effect of oral dehydroepiandrosterone (DHEA) on theurine testosterone/epitestosterone (T/E) ratio in human male volunteers. J Anal Toxicol 1998;22:455-459.


Advertisements

1,4,6 Androstatriene-dione (ATD)

Diagram of molecule

Chemical Name(s):

Androsta-1,4,6-triene-3,17-dione
1,4,6-androstatriene-3,17-dione
Chemical Formula: C19H22O2
Molecular Weight: 282
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 4%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: 2 days
Legal Status (US): Not listed as a controlled substance
Average Dose: 25-100mg/day
Average Cycle Length: 4-8 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

ATD is a steroidal aromatase inhibitor, known as a suicidal inhibitor because it permanently binds to the aromatase enzyme.

ATD is used for its aromatase inhibiting and testosterone boosting effect. Its effectiveness at lowering estrogen appears to be stronger than 6-oxo. It converts to 1,4,6-testosterone, which would also be expected to cause falsely high readings for a testosterone analysis.

The 1,4,6-testosterone metabolite of ATD can also bind to the androgen receptor (AR) and induce androgenic (or possibly anti-androgenic) effects similar to what is seen from 6-oxo. This would be expected since 1,4,6-testosterone has about one third the binding affinity for the AR, therefore it may interefere with the anabolic or androgenic action of hormones which bind the androgen receptor.

ATD would also be expected to interfere with production of natural testosterone by acting upon the hypothalamus pituitary testicular axis (HPTA), therefore this compound should not be used during post cycle therapy (PCT), however it could successfully be used during a cycle to help keep estrogen in control. Anecdotal reports and animal studies have also shown ATD inhibits libido and general sexual potency.

Common Clones:

Arom-X by Advanced Muscle Science (AMS)
AIFM by Anafit
ATD MAX by Anabolic Formulations
ATD-JET by Molecular Developments
Reversitol by IForce


Related Discussion

The Official 1,4,6 Androstatriene-dione (ATD) Thread
Posted by Eric

References

Effect of an inhibitor of aromatization, 1,4,6 androstatriene-3,17-dione (ATD) on LH release and steroid binding in hypothalamus of adult female rats.

Exp Brain Res. 1986;64(3):407-10.
Slama A, Gogan F, Sarrieau A, Vial M, Rostene W, Kordon C.

Effects of ATD on male sexual behavior and androgen receptor binding: a reexamination of the aromatization hypothesis.
ME Kaplan and MY McGinnis
Horm Behav, Mar 1989; 23(1): 10-26.

Anabolic Pharmacology
Seth Roberts (2009)

Cynostane

Diagram of molecule

Chemical Name(s):

2-cyano-17a-methyl-17b-hydroxy-androstan-3-one
2-cyano-17a-methyl-17b-hydroxy-androst-3-one (incorrect name)
Chemical Formula: C21H31NO2
Molecular Weight: 329
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 40%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
40-50mg/day standalone
20-30mg/day when stacking
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

2-cyano-dromostolone is a 17aa molecule relatively new to the scene with very few reviews as of yet.

It has a cyano group attached to the 2 position. The chemical structure is the same as methyldrostanolone (Superdrol), except it has a CN group on the 2 position instead of a methyl group. It is a C-17aa steroid and it will be liver toxic. Although, due to the lack of the 4-ene on ring A and lack of 2-methylation, liver toxicity may be reduced relative to a di-methylated steroid such as Superdrol.

So far, feedback is very limited for this compound. However results would be expected to be fairly lean as this compound cannot convert to estrogen. Based on the chemical structure the anabolic potency would appear to be fairly potent with moderate androgenic potency.

At the time of this writing there was only one manufacturer to bring this product to the market and there seems to have been a nomenclature mistake on the labeling for this steroid. The chemical name contains the term “androst”, assuming that there is some sort of ene group on ring A. But there does not seem to be such mention of an ene group on ring A. Therefore, the term androst should be androstan. But if this is the case, the 2-cyano group needs to be stated as alpha or beta. This makes a big difference, since usually C2-alpha groups are significantly more effective than beta.

There are studies about other 2-cyano steroids such as 2-cyano-DHT and 2-cyano-progesterone. In separate studies, one done on dogs, it was seen that both of these 2-cyano steroids caused inhibition of 3b-HSD enzyme. This inhibition would cause severe adrenal suppression. This is a very unsafe inhibition. Whether it occurs in this cyano steroid is unknown, but users need to be aware of this possibility.

Common Clones:

Cynostane by Anabolic Innovation


Related Discussion

The Official Cynostane Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Methylstenbolone

Diagram of molecule

Chemical Name(s):
2,17a-Dimethyl-17b-hydroxy-5a-androst-1-en-3-one
Chemical Formula: C21H32O2
Molecular Weight: 316.5
CAS: NA
Q Qatio: 3.9
Anabolic #: 660
Androgenic #: 170
Oral Bioavailability: Estimated at 50%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
5-20mg/day standalone
1-5mg/day when stacked
Average Cycle Length: 2-4 weeks

 

Stimulator
Inhibitor

 

 
-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

 

Characteristics

Although this compound cannot convert to estrogen, it will bind strongly to SHBG, thus increasing freely circulating estrogen (and testosterone). While there is a lack of anecdotal feedback from this compound to tell the real world effect this compound may have on causing gyno, experience with related compounds tell us gyno symptoms may occur.

Users should be very careful with methylstenbolone and start out with a very low dose. This compound will likely produce a rapid increase in intracellular water retention by inhibiting 11-beta hydroxylase and building up levels of mineralcorticoids that will encourage sodium and water retention.

Gains upwards of 20-25lbs in 4 weeks are probably possible with this compound. However the liver toxicity issues would likely be the first reason why someone wouldn’t be able to make incredible gains from this compound. For this reason it would be extremely important to pre-condition the liver with a liver protecting supplement prior to cycling this compound, while continuing use throughout the cycle and during PCT.

The strength increases from this compound will likely encourage weight lifting heavier than tendons and joints are prepared to lift. It is recommended to be cautious of this and to naturally build up strength levels prior to cycling this steroid.

Using a low dose of methylstenbolone with a moderate dose of a non-methylated compound would be an acceptable way to try to limit the side-effects from this compound, although caution would still need to be taken for liver health no matter what dose is used.

Because of the strength and weight gain this compound would offer it would likely be best used as part of a bulking cycle.

Availability: 

UltraDrol by Antaeus Labs

Related Discussion

The Official Methylstenbolone Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Furazabol THP

Diagram of molecule

Chemical Name(s):
5a-androstano[2,3-c]furazan-17b-tetrahydropyranol ether
Chemical Formula: C24H36N2O3
Molecular Weight: 401
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 15%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: 2-4 hours
Legal Status (US): Not listed as a controlled substance
Average Dose:
200-300mg/day standalone
100-200mg/day when stacked
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Furazabol THP is the same compound as the illegal anabolic steroid furazabol except it is not 17aa methylated, and instead has a THP ether attached on the 17b position.

Furazabol does not aromatize and also has very minimal bloat. It has a moderately potent androgenic activity, giving it a fairly low risk for gyno or negative effects on the libido. However its androgenic effects may pose a problem for users prone to androgenic related hair loss.

Once the Furazabol THP reaches the stomach, most of the THP-ether is removed by the stomach acid to form the active Furazabol (the non-methylated version). Therefore, topical delivery of this compound is probably not worthwhile. Furazabol has a similar structure to the illegal anabolic steroid stanozolol (Winstrol). The only difference is the pyrazole ring has been replaced with a furazan ring. There is rumor that this compound has benefits for cholesterol levels. While some evidence proves that it can lower total cholesterol, it should be noted that the decrease in cholesterol is mostly due to a decrease in HDL. Therefore, your LDL/HDL ratio would become worse.

Overall this compound produces mild gains, but the side-effects are very mild too. Noticeable gains in lean muscle mass and strength are likely not going to be achieved unless doses of at least 200mg/day are used. Furazabol is going to produce very little water retention, therefore it should produce a lean and vascular appearance. Big increases in weight are not likely to happen with this steroid either, so increased blood pressure and painful back pumps should not be a problem.

The half-life of this compound is short, so dosages should be taken every few hours to keep blood levels stable. Although furazabol can successfully be used as a standalone it can be stacked with other compounds depending on the users goals.

Common Clones:

Furazadrol by Axis Labs
FURUZA-A by Competitive Edge Labs (CEL)
Orastan A by Competitive Edge Labs (CEL)
Winadrol by CTD Labs
Winabol by Generation X Labs
Chlomadrol-50 by German American Technologies (G.A.T.)
Furaguno by Spectra Force


Related Discussion

The Official Furazabol THP Thread
Posted by Eric

References

“Enhancement of fibrinolytic and thrombolytic potential in the rat by treatment with an anabolic steroid, furazabol.”

Kumada T, Abiko Y.
Thromb Haemost. 1976 Nov 30;36(2):451-64.

Methyldrostanolone (Superdrol)

Diagram of molecule

Chemical Name(s):

2a,17a-dimethyl-5a-androst-3-one-17b-ol
2a,17a-dimethyl-etiocholan-3-one-17b-ol
Chemical Formula: C21H34O2
Molecular Weight: 318
CAS: NA
Q Qatio: 20
Anabolic #: 400
Androgenic #: 20
Oral Bioavailability: Estimated at 50%
AR Binding Affinity: NA
SHBG Binding Affinity: High
Half Life: ~8 hours
Legal Status (US): Not listed as a controlled substance
Average Dose:
10-30mg/day standalone
5-10mg/day when stacked
Average Cycle Length: 2-4 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][][][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Methyldrostanolone is a C-17 alpha alkylated steroid, originally developed by the American pharmaceutical company Syntex. This steroid is already active and does not require conversion. Methyldrostanolone is the 17aa version of the injectable steroid drostanolone (Masteron). This extra methylation makes this steroid about 3-4x more anabolic than Masteron, and slightly more anabolic than oxandrolone (Anavar). Due to the dimethylation, the toxicity of methyldrostanolone is greater than most other oral steroids. There have been many reported cases of heptatoxicity with this compound. (1-3)

Despite the fact that methyldrostanolone is a DHT derivative and cannot convert to estrogen, some users have still reported gyno like symptoms during or after a cycle. This effect is likely related to the strong SHBG binding effect and increase in freely circulating estrogen (and testosterone) from SHBG. Gyno symptoms may also be related to the fact that methldrostanolone lacks a strong DHT metabolite to antagonize the effects of estrogen (while also having a relatively low intrinsic androgenic value).

Having a fairly low androgenic value will mean that methyldrostanolone will be light on the hairline for most men. However those susceptible to male pattern baldness may still noticed accelerated hair loss during a cycle.

Because of the di-methylation, methlydrostanolone is considerably more resistant to breakdown, thus more potent per mg than most other steroids. However this makes it more liver toxic than other single methylated 17aa orals. Negative effects on the liver generally manifest as a condition known as reversible cholestasis. This is essentially a slowing or complete blockage of bile acids from the liver. Immediate signs of compromised liver function included reduced appetite and general sickness, which will soon be accompanied by yellowing of the eyes (jaundice), excessive itchiness and very dark urine. If these effects are noticed, methyldrostanolone should be discontinued immediately.

Because the effects on the liver it is very important to use a liver protecting supplement during any methyldrostanolone cycle. If not using a supplement to protect your liver, methyldrostanolone should never be used any longer than 2 weeks, with a maximum cycle length of 4 weeks with liver protection.

Other reversible side effects from methyldrostanolone may include increased blood pressure, reduced HDL cholesterol and lower back pumps.

Results wise, users should expect extreme strength increases and weight gain in a relatively short 2-4 week period. Weight gain upwards of 20lbs in 4 weeks is not unheard of with this incredibly potent compound. Although subcutaneous water gain would be minimal, intramuscular water retention should be expected. This is due to inhibition of 11b-hydroxylase and build-up of mineralcorticoids which encourage salt and water retention within the muscles. The most obvious physical effects will be improved vascularity, aggressive muscular pumps, and oily skin.

While methyldrostanolone can stack well with most other steroids, it should never be stacked with another methylated (17aa) steroid.

Common Clones:


Oxodrol 12 by IDS
Superdrol by Anabolic Xtreme
M-Drol by Competitive Edge Labs (CEL)
SD-1 by Performance Design
Methyl VOL by Engineered Sports Technology (EST)
Revenge SDX by Bioscience Technologies
S-Drol by Nutracoastal
E-Pol by Purus Labs
MethaDROL by IForce
Straight-DROL by Black China Labs
MethylDX3 by Physical Enhancing Industries
Oxevol (same as Dianevol) by Evolution Labs
Beastdrol by Mrsupps



Related Discussion

The Official Methyldrostanolone (Superdrol) Thread
Posted by Eric

References

Cholestatic Jaundice and IgA Nephropathy Induced by OTC Muscle Building Agent Superdrol.

Beata Jasiurkowski MD, et al.
The American Journal of Gastroenterology (2006) 101, 2659-2662;

Severe Cholestasis and Renal Failure Associated with the Use of the Designer Steroid Superdrol (Methasteron): A Case Report and Literature Review
John Nasr and Jawad Ahmad
Digestive Diseases and Sciences

Methasteron-Associated Cholestatic Liver Injury: Clinicopathologic Findings in 5 Cases”
Neeral L. et al.
Clinical Gastroenterology and Hepatology, Volume 6, Issue 2, February 2008, Pages 255-258

Identification of drostanolone and 17-methyldrostanolone metabolites produced by cryopreserved human hepatocytes”
Julie Gauthier, Danielle Goudreault, Donald Poirier and Christiane Ayotte
Steroids; Volume 74, Issue 3, March 2009, Pages 306-314

Androstenetrione (6-OXO)

Diagram of molecule

Chemical Name(s):

4-androsten-3,6,17-trione
3,6,17-androstenetrione
androst-4-ene-3,6,17-trione
6-ketoandrostenedione
Chemical Formula: C19H24O3
Molecular Weight: 300
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 4%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: 3-6 hours
Legal Status (US): Not listed as a controlled substance
Average Dose: 300-600mg/day
Average Cycle Length: 4-8 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

6-OXO is a steroidal aromatase inhibitor, known as a suicidal inhibitor because it permanently binds to the aromatase enzyme.

It is used for its anti-estrogen and testosterone boosting effects.

There is debate about whether or not 6-oxo actually lowers estrogen or increases testosterone. Several human studies have shown an increase in estrone levels following 6-oxo supplementation. However, one of the primary metabolites of 6-oxo is 6-oxoestrone which may have given a false positive for elevated estrone levels. The human study also concluded that 6-oxo raised testosterone levels, however it is possible that 6-oxotestosterone (which is another metabolite of 6-oxo) gave a false positive for the testosterone level as well.

Another interesting element to these articles is that despite the supposed increase in testosterone (enough to cause significant improvements in body composition if given via injection) no improvements where found for fat free mass (FFM) or strength. Therefore, 6-oxo is either a weak AI that doesn’t really inhibit estrogen at the recommended dose and simply converts to metabolites which give false readings, or it actually does increase testosterone, while the 6-oxo metabolites antagonize the androgen receptor enough to block any anabolic effect from testosterone.

Either way, no ergonomic or real world benefit could be found after 6-oxo supplementation.

Its also worth mentioning that 6-oxo should never be used post cycle, as its steroidial effects would likely interfere with recovery of natural testosterone production.


Related Discussion

The Official Androstenetrione (6-OXO) Thread
Posted by Eric

References

Immunological interference of the synthetic aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD) and its metabolite(s) in the radioimmunoassay for testosterone.

MD Donaldson and MG Forest
Steroids, Dec 1980; 36(6): 717-21

Testosterone dose-response relationships in healthy young men
Shalender Bhasin, et al.
Am J Physiol Endocrinol Metab, Dec 2001; 281: E1172 – E1181.

%d bloggers like this: