1-Androsterone

Diagram of molecule

Chemical Name(s):

1-androsten-3b-ol-17-one
1-Dehydroepiandrosterone
Chemical Formula: C19H28O2
Molecular Weight: NA
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 8%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
200-300mg/day Transdermally
400-600mg/day standalone (oral)
200-400mg/day when stacking (oral)
Average Cycle Length: 4-6 weeks

Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

1- Androsteronetm (1-DHEA) is a non-methylated (non 17aa) pro-steroid that must convert to 1-androstenediol (1-AD), 1-androstenedione (original 1-AD) and/or 1-testosterone to be active. The double bond in the 1st position seems to slightly enhance its ability to resist excretion by the liver.

1-Androsterone occurs naturally in the body, and is a naturally occurring metabolite of DHEA. (2) The 17b-HSD enzyme converts 1-Androsterone to 1-Androstenediol, and the 3b-HSD converts it to 1-Androstenedione. Both of these 1-AD metabolites can then be converted to 1-Testosterone. Although the 1-AD metabolites are known to have some anabolic and androgenic effects on their own, 1-Testosterone is probably where most of the effects come from with this steroid.

There is no conversion to estrogen so users will not experience bloat with this compound, nor will it have a dramatic effect on blood pressure. However one unique side effect that users have reported with this compound is a feeling of lethargy. (It appears that stacking 1-Androsterone with a nuero-active hormone such as DHEA can help reverse this effect)

1-Androsterone (and primarily its metabolites) have relatively potent androgenic effects, therefore gyno is almost never an issue. However, because of the androgenic potency, this compound could pose a mild hair loss risk for those prone to MPB. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.

Results from this compound generally take a couple weeks to be realized. Moderate gains of lean muscle mass and strength can be expected, but users should not expect rapid increases in size or weight with this compound since extra-cellular and intra-cellular water retention are very minimal. This makes the gains from this steroid fairly easy to maintain post cycle.

1-Androsterone will stack well with almost any compound. For more dramatic gains in size and strength it is recommended to stack this compound with an aromatizing steroid or possibly one of the progestational compounds listed elsewhere.

Common Clones:

1-T by Primordial Performance
1-Androsterone by Advanced Muscle Science (AMS)

Related Discussion

The Official 1-Androsterone Thread
Posted by Eric

References

1. 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties.

A Friedel, et al.
Toxicol Lett, Aug 2006; 165(2): 149-55.

2. “Metabolism of 1-Dehydroandrostanes in Man”
Galletti and Gardi, et al.
J Steroid Biochem, 3 (1972), 933-936

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1,4-AD (Boldione)

Diagram of molecule

Chemical Name(s):

1,4-androstadiene-3b,17b-dione
androst-1,4-diene-3b,17b-dione
1,4-Androstenedione
Chemical Formula: C19H24O2
Molecular Weight: 284.4
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 8%
AR Binding Affinity: NA
SHBG Binding Affinity: Low
Half Life: NA
Legal Status (US): Listed as a controlled substance
Average Dose:
800-1500mg/day standalone
400-1000mg/day when stacking
Average Cycle Length: 6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Boldione is NOT a 17-alpha alkylated steroid, therefore high doses must be taken to accommodate for its rapid excretion from the liver.

Boldione itself likely does not have any significant anabolic or androgenic value. However after interaction with the 17b-HSD enzyme, boldione is converted to the illegal anabolic steroid boldenone. Boldione can also be converted to 1-androstenedione (1-AD) and/or 1-testosterone after interaction with the 5a-reductase enzyme. These metabolites are where this pro-hormone gets most of its effects.

Since boldione is a dione, conversions to the more powerful steroid metabolites are expected to be near 15-20%, which is another reason why such high doses are needed to see results.

This pro-hormone (and its metabolites) do not convert very readily to estrogen, so an aromatase inhibitor would likely not be needed during a cycle.

Results can be expected to kick in slowly after several weeks. Moderate gains in size and strength should be expected. This compound also has a tendency to increase appetite, which makes it a good choice for bulking.

Side effects are minimal with boldione, but can become more noticeable with doses above 1000mg/day. Side-effects may include increases blood pressure and oily skin. Overall, results and side-effects would be similar to that of boldenone, including lean mass gains with low bloating. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.

Although this compound can be used as a standalone, it is recommended to stack this compound with an already active steroid, as the high doses of boldione will likely saturate most of the steroid conversion enzymes.

Common Clones:

BOLD by IForce
EQ-Plex by Competitive Edge Labs (CEL)
BOLD 200 by IForce
EQ-Jet by Molecular Development
P-Bold by Proven Products


Related Discussion

The Official 1,4-AD (Boldione) Thread
Posted by Eric

References

“Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle: 1. Metabolite profiles of boldenone, boldenone esters and boldione in cattle urine.”

Bruno Le Bizec, Frédérique Courant, Isabelle Gaudin, Emanuelle Bichon, Blandine Destrez,
Robert Schilt, Rosa Draisci, Fabrice Monteau and François André
Steroids; Volume 71, Issues 13-14, December 2006, Pages 1078-1087


“An
in vitro study on metabolism of 17β-boldenone and boldione using cattle liver and kidney subcellular fractions”
R. Merlanti, G. Gallina, F. Capolongo, L. Contiero, G. Biancotto, M. Dacasto and C. Montesissa

“Pathology of the testicle and sex accessory glands following the administration of boldenone and boldione as growth promoters in veal calves”
Cannizzo, F.T.(Universita degli Studi di Torino (Italy)); Zancanaro, G.; Spada, F.; Mulasso, C.; Biolatti
Nov 2007 Veterinary science and hygiene

Methoxygonadiene

Diagram of molecule

Chemical Name(s):

13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one
13b-ethyl-3-methoxy-2,5 (10)-gona-diene-17-one
Chemical Formula: C20H28O2
Molecular Weight: 300
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 20%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
50-75mg/day standalone
25-50mg/day when stacked
Average Cycle Length: 4 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Methoxygonadiene is not a 17aa steroid so liver toxicity is not as harsh as with 17aa steorids, however the ethyl group on C-18 may make it slightly more toxic than a non-ethylated steroid (while increasing its oral bio-availability). The progestational activity of methoxygonadiene (once it is converted to its active metabolites) is considered to be slightly stronger than nandrolone.

In the stomach acid, the C-3 methoxy group is rapidly cleaved off and the double bond on the A ring at C-2 is lost. At this point, a 3-oxo is formed and a metabolite known as 13b-ethyl-nor-androstenedione is created, which is chemically similar to norbolethone, and probably where this compound gets most of its effects.

13b-ethyl-nor-androstenedione is about equal to testosterone in anabolic potency, yet less androgenic. This would make this compound fairly light on the hairline with minimal chance of acne or other androgenic side-effects.

With low androgenic activity, this compound may negatively affect the libido and erectile function. The lack of androgenic potency and progestational effects make this compound likely to cause gyno symptoms. Users could stack this compound with testosterone or one of its non-aromatizing metabolites to preserve DHT levels and possibly prevent these side-effects.

Users experience rapid weight gain from this compound partly due to subcutaneous water retention from the progestational activity. Therefore the overall gains from this compound may lead to a bloated appearance. Because of the progestational effects, users should avoid stacking this compound with other gyno aggravating compounds. Methoxygonadiene can aromatize to estrogen in small amounts, however not to any significant degree, therefore an aromatase inhibitor would provide little protection against this compounds side-effects.

Common Clones:

Revolt by KiloSports
M-LMG by Competitive Edge Labs (CEL)
X-MASS by Generic Labs
Deiselbolan by Mrsupps


Related Discussion

The Official Methoxygonadiene Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Halodrol

Diagram of molecule

Chemical Name(s):
4-chloro-17a-methyl-androst-1,4-diene-3b,17b-diol
Chemical Formula: C20H29C1O2
Molecular Weight: 337
CAS: NA
Q Qatio: 2.6
Anabolic #: 74
Androgenic #: 28
Oral Bioavailability: Estimated at 40%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: ~16 hours
Legal Status (US): Not listed as a controlled substance
Average Dose:
100-150mg/day standalone
50-100mg/day when stacking
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[][][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

Halodrol is a 17aa steroid that converts to the steroid oral Turinabol after interaction with 3b-HSD at an estimated rate of about 5%.

Because of this low conversion, doses must be higher than other 17aa pro-steroids. However, it is suspected that Halodrol has decent potency without conversion as good results are seen despite the relatively low conversion to Turinabol. Based on Vida’s data Halodrol appears to be about as potent as testosterone, and significantly less androgenic.

Because of the 4-chloro group, halodrol has no progestational effects, it cannot interact with the aromatase enzyme, and it produces inactive 4-chloro-DHT metabolites. This makes androgenic side-effects such as hair loss, high blood pressure, acne and prostate enlargement less likely. Anecdotal reports would also have us believe that side-effects with this compound are fairly mild.

Although caution would still need to be had, the low androgenic value of this compound would also make it one of the more appropriate anabolic steroids for women wishing increase lean mass yet avoid a deeper voice, increased hair growth, acne and clitoral growth. (Oral Turinabol was actually the preferred steroid for Olympic female athletes in East Germany)

The lack of androgenic potency might be expected to create problems with gyno, however the low SHBG binding affinity has minimal interference with SHBG levels and/or freely circuiting estrogen and testosterone. It does not appear that halodrol has a significant gyno risk.

Because halodrol must be used at such a high dose to see noticeable effects, liver toxicity may become an issue. Therefore it is recommended to use a liver protecting supplement before and during halodrol cycles.

Gains from Halodrol generally take a few weeks to notice, but users can expect solid increases in strength, lean muscle mass, improved vascularity and minimal water retention. This allows some of the gains to be kept after the cycle if good diet and training are continued. Quick dramatic gains in size and strength are not generally noticed with Halodrol.

It is used successfully as a standalone, but would be expected to stack well with most other steroids, except 17aa oral due to liver toxicity concerns.

Common Clones:

Halo-MASS by Anabolic Formulations
HD-1 by Performance Design
H-Drol by Competitive Edge Labs (CEL)
Halovar by Purus Labs
Hemadrol by Engineered Sports Technology (EST)
Halodrol-50 by Gaspari Nutrition
Oral Turinadrol by Juggernaut Nutrition
Super Halo by Black China Labs
H-Drol by Nutracoastal
Helladrol by Mrsupps


Related Discussion

The Official Halodrol Thread
Posted by Eric

References

“Hepatotoxicity Associated With Dietary Supplements Containing Anabolic Steroids”

Michel I. Kafrouni, Robert A. Anders and Sumita Verma
Clinical Gastroenterology and Hepatology; Volume 5, Issue 7, July 2007, Pages 809-812

4-DHEA

Diagram of molecule

Chemical Name(s):

1-androsten-3b-ol-17-one
4-Dehydroepiandrosterone
Chemical Formula: C19H28O2
Molecular Weight: 288
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 4%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
500-1000mg/day standalone
200-500mg/day when stacked
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

4-DHEA is a naturally occurring non-methylated (non-17aa) pro-steroid.

4-DHEA, like DHEA, requires a 2 step conversion process involving 3b-HSD and 17b-HSD to convert it to Androstenedione/androstenediol, and then testosterone. What makes 4-DHEA slightly different from DHEA is a double bond in the 4th position rather than the 5th. This makes 4-DHEA less estrogenic by not acting directly upon the estrogen receptor like DHEA has been found to do.

Although 4-DHEA can aromatize to estrogen it is probably not enough to cause high estrogen related side-effects.

Overall results will be similar to or the original 4-AD banned back in 2004. Higher doses of this compound will produce fairly lean gains in muscle mass, with moderate improvements in strength. This product may produce some bloat from the estrogen conversion, which could be countered by administering an aromatase inhibitor, but this will largely defeat the purpose of using this compound to begin with.

Since this compound is naturally occurring and non-methylated overall side-effects will be fairly mild. However, high doses may also lead to oily skin, acne and increased blood pressure. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.

Because this compound can convert to testosterone it can also convert to DHT and other 5a-reduced metabolites. This can serve as a good stack with progestational or relatively non-androgenic compounds that may create problems with libido or gyno because of lacking androgenic potency.

Although this compound is relatively safe and moderately effective, its high cost has probably been the reason for its lack of popularity.

Common Clones:

4-AD UTT by Advanced Muscle Science (AMS)


Related Discussion

The Official 4-DHEA Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

norDHEA

Diagram of molecule

Chemical Name(s):

5-estren-3b-ol-17-one
Nordehydroepiandrosterone
Chemical Formula: C18H26O2
Molecular Weight: 274
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 4%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance
Average Dose:
300-600mg/day standalone
200-300mg/day when stacked
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
2
3
4
5

Muscle Gain

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Strength Gain

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Fat Gain (negative indicates fat loss)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Water Retention (extra-cellular bloat)

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Aggression

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Libido

[][]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Acne

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Hair Loss

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Prostate Enlargement

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Liver Toxicity

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Lethargy

[]
-5
-4
-3
-2
-1

0
1
2
3
4
5

Characteristics

norDHEA is a non-methylated (non-17aa) pro-steroid. (naturally occurring in trace amounts in humans)

norDHEA can convert to the illegal anabolic steroid nandrolone by converting to norandrostenediol/norandrostenedione, and then to nandrolone. Nandrolone is known to have stronger anabolic effects than testosterone, yet weaker androgenic effects.

norDHEA will aromatize to estrogen less than regular DHEA, but because it is a nor compound it lacks strong androgenic metabolites. For instance, after nandrolone interacts with 5a-reductase, the metabolite dihydronandrolone (DHN) is formed, which is a weaker nor-version of DHT.

Ironically, the lack of estrogen conversion from norDHEA is probably balanced by the lack of androgenic potency and progestational effects, which makes the possibility of bloating and experiencing gyno about as likely as with regular DHEA.

One difference between norDHEA and DHEA that should be considered is the fact that norDHEA will have less androgenic effects, which may pose less risk of androgenic related hair loss and/or acne. This may be a smart choice for some men, and a decent choice for women looking for a moderately anabolic compound without much androgenic effect. (to avoid masculinizing side-effects)

Because of the low bio-availability, high doses must be used to notice gains in lean muscle mass and strength. Even with higher doses, the gains will be mild to moderate. Some bloat should be expected from the estrogenic and progestational effects of the nor-steroids. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.

Like the other DHEA derivatives, norDHEA would be useful in a transdermal application since the enzymes needed for the conversions to more powerful metabolites are concentrated in the skin and absorption through the skin using a good transdermal delivery cream could allow for 5-10x higher absorption than oral.

This compound would stack well with almost any other steroid, except those with progestational activity.

Common Clones:

Decavol by Advanced Muscle Science (AMS)


Related Discussion

The Official norDHEA Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

Dienedione (Tren)

Diagram of molecule

Chemical Name(s):

19-norandrosta-4,9-diene-3b,17b-dione
estra-4,9-diene-3b,17b-dione
4,9 Estra
Chemical Formula: C18H22O2
Molecular Weight: 270
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 20%
AR Binding Affinity: 5
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Listed as a controlled substance
Average Dose:
100-200mg/day standalone
50-100mg/day when stacking
Average Cycle Length: 4-6 weeks
Stimulator
Inhibitor

-5
-4
-3
-2
-1

0
1
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4
5

Muscle Gain

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-5
-4
-3
-2
-1

0
1
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5

Strength Gain

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-5
-4
-3
-2
-1

0
1
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4
5

Fat Gain (negative indicates fat loss)

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-5
-4
-3
-2
-1

0
1
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3
4
5

Water Retention (extra-cellular bloat)

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-5
-4
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-2
-1

0
1
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4
5

Aggression

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-5
-4
-3
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-1

0
1
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4
5

Libido

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-5
-4
-3
-2
-1

0
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4
5

Acne

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-5
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-1

0
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Hair Loss

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-5
-4
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-1

0
1
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5

Prostate Enlargement

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-5
-4
-3
-2
-1

0
1
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4
5

Liver Toxicity

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-5
-4
-3
-2
-1

0
1
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4
5

Lethargy

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-5
-4
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-2
-1

0
1
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5

Characteristics

Dienedione is a non-methylated steroid that converts to a steroid known as 17b-hydroxy-estra-4,9,(10)-dien-3-one (dienolone).

Although dienedione may have some anabolic activity on its own, it gets most of its effects from conversion to dienedrone by interaction with 17b-HSD. This steroids overall effects are somewhere between trenbolone and nandrolone.

Dienedione is known for causing night sweats via its powerful thermogenic effects similar to trenbolone. This thermogenic effect makes dienedione an excellent choice for dropping bodyfat during cutting cycles.

As a 19-nor this compound has decent progestational effects which may lead to gyno symptoms, libido loss and aggressive mood swings. Part of the reason gyno may be a problem with this compound is also because it lacks androgenic potency and down-regulates DHT levels during cycle, which is the body’s natural estrogen blocker.

Dienedione does not convert to estrogen, although it can still lead to the side-effects mentioned above. Because this compound is not 17aa liver toxicity is not really a concern. However some users have reported elevated liver enzyme values during cycle, although this could be related to other factors.

Users usually experience rapid gains in strength and aggression, followed by significant weight gain after several weeks. The results are generally fairly lean with only minor bloat due to the progestational effects.

Dienedione can be used as a standalone. In an effort to prevent libido loss and gyno, it may be stacked with testosterone or one of its non-aromatizing metabolites to help keep DHT levels elevated during cycle.

Common Clones:

Dienedrone by Advanced Muscle Science (AMS)
Liquidrone UTT by Advanced Muscle Science (AMS)
X-Tren by Competitive Edge Labs (CEL)
Tren Xtreme by American Cellular Labs
Tren 250 by Genetic Edge Technologies (GET)
Trena by Nutracoastal


Related Discussion

The Official Dienedione (Tren) Thread
Posted by Eric

References

Anabolic Pharmacology
Seth Roberts (2009)

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