Carbohydrates Can Cause Stiff Joints and Wrinkled Skin

Carbohydrates can cause stiff joints and wrinkled skinNovember 25th, 2009 – Yes, you read that right. Excessive carbohydrate consumption can speed up the aging process by producing nasty molecules called advanced glycation end-products.

Advanced glycation end products (AGE) form in the body when glucose (carbs) attaches itself to a protein (a process called glycation) without enzymatic control.  The more glucose in the blood, the more this process occurs, and the harder it is for the body to reverse the process and/or dispose of harmful AGEs.(1)

Collagen proteins, found in skin, tendons, cartilage, and bones are especially prone to injurious affliction from these glycosalated molecules. As AGEs build up and cause damage to this bodily tissue, the skin will toughen and appear leathery, and joints will stiffen. (1) AGE have also been linked to other age related diseases such as Alzheimer’s disease, cataracts, diabetes, and atherosclerosis to name a few. (3)

Reducing advanced glycation end-products will involve consuming less high glycemic carbohydrates, or making sure you reduce you blood sugar by burning it off shortly after consuming a high carbohydrate meal.

References –

1. The Carbohydrate Hypothesis
Gary Taubes
Good Calories Bad Calories 2007 Pages 191-193

2. Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose.
Toma L, Stancu CS, Botez GM, Sima AV, Simionescu M.
Biochem Biophys Res Commun. 2009 Oct 19 PMID: 19850013

3. Advanced glycation and lipoxidation end products–amplifiers of inflammation: the role of food
Gil A, Bengmark S.
Nutrition Hosp. 2007 Nov-Dec;22(6):625-40 PMID: 18051988

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